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Dr. Soheil Meshinchi is the recipient of the second José Carreras International Fellowship to be awarded this year.

Born in Tehran, Iran, Dr. Meshinchi moved to the United States in 1978 and received his education in the U.S. He obtained his Ph.D. in 1990 from the University of Michigan in Ann Arbor, and his M.D. degree in 1994 from Wayne State University in Detroit. He has been a teaching assistant in both pharmacology and genetics and also has obtained his Board Certification in the specialty of Pediatrics.

Dr. Meshinchi will be working in the laboratory of Dr. Jerald Radich at the Fred Hutchinson Cancer Research Center. Their work is aimed at clarifying the biologic and clinical importance of a mutation in the Flt3 gene, a receptor gene, in children with acute myeloid leukemia (AML). They are part of the Children’s Cancer Group (CCG), an affiliation of institutions using common protocols to treat cancers in children with the aim to collect data from participating groups, analyze results and design new therapies based on these data. The CCG will provide specimens of blood and marrow from AML patients for determination of the prevalence of Flt3. These findings can then be correlated with clinical information to determine the significance of this gene in the outcome of the disease. The work may provide significant insight into the biology of AML and may provide a marker for determining patients with a poor prognosis. Such patients would then be candidates for more aggressive therapy and innovative treatment options.

Dr. Meshinchi is married to Beth Ebel, also a pediatrician, who is currently the holder of a fellowship in the area of violence and injury prevention. The couple is expecting their first child in May. They have enjoyed exploring the outdoor riches of the Seattle area and are looking forward to taking their baby camping with them.